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Psychiatric Disturbances: |
Social Deficits, Social withdrawal Mercury |
Repetitive, perseverative, stereotyped behaviors; OCD-typical behaviors Mercury |
Depression, mood swings, flat affect; impaired facial recognition Arsenic, Copper, Lead, Mercury |
Schizoid tendencies; hallucinations; delirium Mercury |
Irritability, aggressive behaviors, temper tantrums Lead, Mercury |
Suicidal Behaviors Copper, Mercury |
Sleep difficulties/ disturbances Lead, Mercury, Thallium |
Chronic fatigue (CFS); weakness, malaise Aluminum, Arsenic, Cadmium, Copper, Lead, Mercury, Thallium |
Anorexia; symptoms reflecting eating disorders, loss of appetite/weight Arsenic, Lead, Mercury |
Anxiety; nervous tendencies Thallium |
Attentional problems (ADHD), lacks eye contact, impaired visual fixation Lead, Mercury |
Speech and Language Deficits: |
Speech disorders Aluminum, Mercury |
Loss of speech, developmental problems with language Mercury |
Speech comprehension deficits Mercury |
Dysarthria; articulation problems; slurred speech, unintelligible speech Mercury |
Cognitive Impairments: |
Mental retardation, borderline intelligence Arsenic, Lead, Mercury |
Uneven performance on IQ scores, low IQ scores Copper, Lead |
Poor concentration, attention deficits (ADHD), response inhibition Aluminum, Lead |
Poor memory (short term, verbal, and auditory) Aluminum, Lead |
Difficulties understanding abstract ideas; difficulty carrying out complex commands X Metals |
Dementia; pre-senile and senile dementia Aluminum |
Stupor Aluminum, Arsenic |
Impaired reaction time; lower performance on timed tests Lead |
Sensory Abnormalities: |
Abnormal Sensations in the mouth and extremities Arsenic |
Hearing loss, difficulty hearing Arsenic, Lead, Mercury |
Abnormal touch sensations; diminished touch sensations, aversion to touch Arsenic |
Blurred vision; sensitivity to light Arsenic, Mercury |
Motor Disorders: |
Choreiform movements, myoclonal jerks, unusual postures Copper, Mercury |
Difficulty walking, swallowing, talking Copper, Mercury |
Flapping, circling, rocking, toe walking Mercury |
Problems with intentional movements or imitation Mercury |
Abnormal gait/posture; incoordination, loss of balance; problems sitting, lying, crawling, and walking Mercury |
Decreased locomotor activity Aluminum, Arsenic |
Convulsions; seizure Aluminum , Arsenic, Copper, Lead, Mercury, Thallium |
Physiological Impairment |
Brain and Central Nervous System: |
Neurofibrillary tangles Aluminum |
Neuritis, retrobulbar neuritis; neuropathy Aluminum, Arsenic, Thallium |
| Encephalopathy Aluminum, Arsenic, Lead, Thallium |
Cerebrovascular disease X Metals |
Alterations in nerve conduction velocity Lead |
Alterations in the spinal chord Thallium |
Accumulates in CNS structures Aluminum, Mercury |
Abnormal EEGs Arsenic, Lead |
Autonomic disturbances Copper, Lead, Mercury, Thallium |
Peripheral Nervous System: |
Peripheral neuropathy Arsenic, Mercury |
Alterations in peripheral nerves Arsenic |
Loss of feeling/ numbness in the extremities; paresthesia Arsenic, Mercury, Thallium |
Gastrointestinal Tract: |
Nausea, vomiting, diarrhea; loss of appetite Arsenic, Copper, Mercury, Thallium |
Abdominal pain, stomach cramps; burning of the throat and mouth Arsenic, Copper, Lead, Mercury, Thallium |
Esophagitis; gastroenteritis; colitis Arsenic, Mercury, Thallium |
Cancers (colon, pancreatic, stomach, or rectal) Arsenic |
Renal and Hepatic Impairment: |
Hepatotoxicity; Liver dysfunction, damage Arsenic, Copper, Thallium |
Cirrhosis of the liver; hepatitis Copper |
Kidney disease ; kidney failure Arsenic, Lead, Mercury |
Renal toxicity; tubular proteinosis Arsenic, Copper, Lead |
Kidney Damage, histological alterations Arsenic, Lead |
Cardiovascular System: |
Blood vessel damage Arsenic |
Anemia; decreased red blood cell count Arsenic, Copper, Lead |
Hypertension; increased heart rate (tachycardia) Arsenic, Copper, Lead, Thallium |
Electrocardiac disorders |
Peripheral vascular disease; cardiovascular disease; vascular collapse Arsenic, Lead |
Respiratory System: |
Pulmonary Fibrosis Aluminum, Arsenic |
Pulmonary edema X Metals |
Pneumonia, laryngitis, pharyngitis, bronchitis Aluminum, Arsenic, Mercury |
Restrictive airway disorders, asthmatic conditions, pneumoconisis Arsenic, Aluminum |
Respiratory tract cancers Arsenic |
Nasal ulcers, perforation of the nasal septum X Metals |
Immune System |
Increased incidences of asthma, autoimmune-like symptoms, allergies & inhibition of lymphocytes, T-cells, monocytes X metals |
Immunosuppression Lead |
Decreased white blood cell count Arsenic, Thallium |
Reproductive System: |
Genital abnormalities Aluminum, Thallium |
Disturbances in menstrual cycle; menstrual pains Copper, Mercury |
Birth defects; premature births; Spontaneous abortion Arsenic, Lead, Mercury |
Reproductive dysfunction Arsenic, Aluminum, Cadmium, Lead |
Other Physical Disturbances: |
Hypotonia or hypertonia; decreased muscular strength X Metals |
Rashes, contact dermatitis, eczema, itchy/irritating skin Aluminum, Arsenic, Copper, Mercury |
Muscle pain; headache; acrodynia; colic Arsenic, Copper, Lead, Thallium |
Alopecia (hair loss) Thallium |
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